UNCOMMON ANORECTAL PATHOLOGY: ANORECTAL MELANOMA

Anorectal melanoma (AM) is a rare and aggressive tumor, characterized by poor prognosis. It accounts for 0.4–1.6% of all melanomas, only 1% anorectal malignant tumors [1]. difficult to diagnose due the hidden site nonspecific symptoms, occurring usually at late stage. The most common symptom rectal bleeding. There are various histological variants AM. currently no consensus treatment typical therapeutic approach remains surgical resection however, this not associated with improved overall survival [2,3]. We present case 52-year old male complaining bleeding pain about 4 months, which were attributed hemorrhoids. Rectal examination revealed an irregular mass near anal verge. Biopsies taken analysis, they fixed in 10% formalin, paraffin embedded routinely stained Hematoxylin– Eosin. Immunohistochemical investigations done using antibodies against cytokeratin (CK), P40, HMB45 Melan A.